This study aimed to evaluate the effects of Trichoderma sp. coating and Tithonia compost application on potato growth and production. The research was conducted in Pattapang Village, Tinggimoncong District, Gowa Regency, from January 2023 to November 2023. This study was designed in a factorial design with two factors. The first factor was the coating, which consisted of no coating and with coating. The second factor was the dosage of Tithonia compost, which included 0 kg/plot, 3 kg/plot, 6 kg/plot, 9 kg/plot, and 12 kg/plot. Based on the research results, the interaction between Trichoderma sp. coating and Tithonia compost application had a significant effect on plant height, leaf number, tuber number, tuber weight, stomatal opening area, stomatal density, and chlorophyll content (a, b, and total). The effect of Tithonia compost dosage was significant on tuber diameter and tuber length. Additionally, the effect of Trichoderma sp. coating was significant on vitamin C content.\r\nKeywords: Coating, compost, potato, Trichoderma sp., tuber, Tithonia compost, Potato growth, Potato production, Coating effects, Factorial design, Plant height, Leaf number.\r\n